近五年发表SCI论文400余篇,其中ESI热点论文2篇,ESI高被引论文7篇。相继在临床药理、抗炎免疫药理、肝脏药理、天然药物活性成分分析及中药复方的代谢研究、计算机辅助药物设计、先导化合物的发现和结构优化、机制导向的新药设计与发现等领域发表多项重要原创研究成果。另有7位教授成为20个如《Hepatology》、《Gut》、《Am J Pathol》等世界知名期刊的审稿专家。
代表性论文(倒序)
一. ESI热点论文(2篇):
1. Meng XM, Nikolic-Paterson DJ, Lan HY.TGF-β: the master regulator of fibrosis. Nat Rev Nephrol.2016 Jun;12(6):325-38.
2. Yang SM, Huang C, Li XF, Yu MZ, He Y, Li J. miR-21 confers cisplatin resistance in gastric cancer cells by regulating PTEN. Toxicology. 2013 Apr 5;306:162-8. doi: 10.1016/j.tox.2013.02.014.
二.ESI高被引论文(7篇):
1. Cai S, Cheng X, Pan X, Li J. Emerging role of exosomes in liver physiology and pathology. Hepatol Res. 2016 Aug 18. doi: 10.1111/hepr.12794.
2.Zhang H, Shang YP, Chen HY, Li J. Histone deacetylases function as novel potential therapeutic targets for cancer. Hepatol Res. 2016 Jul 26. doi: 10.1111/ hepr. 12757.
3. Meng XM, Nikolic-Paterson DJ, Lan HY.TGF-β: the master regulator of fibrosis. Nat Rev Nephrol.2016 Jun;12(6):325-38.
4. Chen ZL, Shi TL, Zhang L, Chen ZL ,Shi TL, Zhang L ,Zhu PL, Deng MY, Huang C, Hu TT, Jiang L, Li J.Mammalian drug efflux transporters of the ATP binding cassette (ABC) family in multidrug resistance: A review of the past decade. Cancer Lett. 2016 Jan 1;370(1):153-64.
5. Meng XM, Tang PM, Li J, Lan HY. TGF-β/Smad signaling in renal fibrosis.Front Physiol. 2015 Mar 19;6:82. doi: 10.3389/fphys.2015.00082.
6. Meng XM, Nikolic-Paterson DJ, Lan HY. Inflammatory processes in renal fibrosis. Nat Rev Nephrol. 2014;10,493-503.
7. He Y, Meng XM, Huang C, Wu BM, Zhang L, Lv XW, Li J. Long noncoding RNAs: Novel insights into hepatocelluar carcinoma. Cancer Lett. 2014 Mar 1;344(1):20-27.
三.其他代表性论文
1. Zhang QL, Fu BM, Zhang ZJ. Borneol, a novel agent that improves central nervous system drug delivery by enhancing blood-brain barrier permeability. Drug Deliv. 2017 Nov;24(1):1037-1044.
2. Ma T, Huang C, Xu Q, Yang Y, Liu Y, Meng X, Li J, Ye M, Liang H. Suppression of BMP-7 by histone deacetylase 2 promoted apoptosis of renal tubular epithelial cells in acute kidney injury. Cell Death Dis. 2017 Oct 26;8(10):e3139.
3. Cheng X, Shi JB, Liu H, Chen LZ, Wang Y, Tang WJ, Liu XH. Discovery of (4-bromophenyl) (3-hydroxy-4-methoxyphenyl) methanone through upregulating hTERT induces cell apoptosis and ERS. Cell Death Dis. 2017 Aug 24;8(8):e3016.
4. He Y, Feng D, Li M, Gao Y, Ramirez T, Cao H, Kim SJ, Yang Y, Cai Y, Ju C, Wang H, Li J, Gao B. Hepatic mitochondrial DNA/Toll-like receptor 9/MicroRNA- 223 forms a negative feedback loop to limit neutrophil overactivation and acetaminophen hepatotoxicity in mice. Hepatology. 2017 Jul;66(1):220-234.
5. Wang N, Zhen Y, Jin Y, Wang X, Li N, Jiang S, Wang T. Combining different types of multifunctional liposomes loaded with ammonium bicarbonate to fabricate microneedle arrays as a vaginal mucosal vaccine adjuvant-dual delivery system (VADDS). J Control Release. 2017 Jan 28;246:12-29.
6. Peng YY, He YH, Chen C, Xu T, Li L, Ni MM, Meng XM, Huang C, Li J. NLRC5 regulates cell proliferation, migration and invasion in hepatocellular carcinoma by targeting the Wnt/β-catenin signaling pathway. Cancer Lett. 2016 Jun 28;376(1):10-21.
7. Tang J, Liu Z, Ji F, Li Y, Liu J, Song J, Li J, Zhou J. The role of the cell cycle in the cellular uptake of folate-modified poly(L-amino acid) micelles in a cell population. Nanoscale. 2015 Dec 28;7(48):20397-404.
8. Ge JF, Gao WC, Cheng WM, Lu WL, Tang J, Peng L, Li N, Chen FH. Orcinol glucoside produces antidepressant effects by blocking the behavioural and neuronal deficits caused by chronic stress. Eur Neuropsychopharmacol. 2014 Jan;24(1):172-80.