徐有翠,博士,副教授,硕士生导师
1994年08月出生,博士毕业于中国科学技术大学(导师:王育才),中国科学技术大学附属第一医院及广东省人民医院完成博士后训练(合作导师:王育才、朱晨、温龙平)。2023年12月至今,任职于安徽医科大学药学院。主要研究方向为脏器(肾脏、肝脏)损伤炎性微环境的活体显微成像分析、纳米治疗药物开发及机理解析;肿瘤及炎症性疾病(脏器损伤、细菌感染等)诊疗纳米药物及新型疫苗系统的开发。主持或参与中国博士后科学基金特别资助、国家自然科学基金面上项目等多项科研项目,以第一作者或通讯作者在Nano Letters 、Small 、Autophagy 、Chemical Engineering Journal 、Journal of Controlled Release、 Biomaterials Research等期刊发表研究论文多篇。
主持或参与的科研项目:
(1)中国博士后科学基金特别资助项目,202301-202312,主持;
(2)国家自然科学基金面上项目,201901-202212,参与;
(3)国家自然科学基金面上项目,201801-202112,参与;
(4)2023年引进人才博士科研启动经费。
近五年主要学术论文:
1. Xu Y, Chen J*, Jiang W, Zhao Y, Yang C, Wu Y, Li Q, Zhu C*. Multiplexing Nanodrug Ameliorates Liver Fibrosis via ROS Elimination and Inflammation Suppression. Small, 2022, e2102848. [IF:13.3,中科院一区,TOP期刊]
2. Xu Y#, Yang C#, Wu Y, Jiang W, Cheng Q, Yan L, Chen K*, Wang Y*. In Situ Albumin-hitchhiking NIR-II Probes for Accurate Detection of Micrometastases. Nano Letters, 2023, 23, 5731-5737. [IF: 10.8,中科院一区,TOP期刊]
3. Xu Y#, Wu Y#, Hu Y#, Xu M, Liu Y, Ding Y, Chen J, Huang X, Wen LP*, Li J* & Zhu C*. Bacteria-based Multiplex System Eradicates Recurrent Infection with Drug-resistant Bacteria via Photothermal Killing and Protective Immunity Elicitation. Biomaterials Research, 2023, 27, 27. [IF: 11.3,中科院一区]
4. Chen J#*, Zhang X, Zhang J, Wang Z, Zhu G, Geng M, Zhu J, Chen Y, Wang W*, Xu Y*. Multifunctional Responsive Hydrogel System for Synergistic Reoxygenation and Chemo/Photothermal Therapy of Metastatic Breast Cancer and Wound Infection. Journal of Controlled Release, 2024, 365, 74-88. [IF:10.8,中科院一区,TOP期刊]
5. Zhang W#, Wei P#, Liu L#, Ding T, Yang Y, Jin P, Zhang L, Zhao Z, Wang M, Hu B, Jin X, Xu Z, Zhang H, Song Y, Wang L, Zhong S, Chen J, Yang Z, Chen Z, Wu Y, Ye Z, Xu Y*, Zhang Y* & Wen LP*. AIE-enabled Transfection-free Identification and Isolation of Viable Cell Subpopulations Differing in the Level of Autophagy. Autophagy, 2, 1-17. [IF:13.3,中科院一区,TOP期刊]
6. Xie C#, Xu Y#, Liu Y, Chen M, Du P, Zhang Y*, Ma X*, Yang S*. Edge-Selective Covalent Passivation of Black Phosphorus Nanosheets by Fullerene C70 toward Enhanced Antimicrobial Performance [J]. Chemical Engineering Journal, 2023, 477, 146997. [IF:15.1,中科院一区,TOP期刊]
7. Odda A H#, Xu Y#, Lin J*, Wang G, Ullah N, Zeb A, Liang K, Wen LP*, Xu AW*. Plasmonic MoO3−x NanoparticlesIncorporatedinPrussianBlue FrameworksExhibitHighlyEfficient Dual Photothermal/Photodynamic Therapy. Journal of Materials Chemistry B, 2019, 7, 2032-2042. [IF:7.0,中科院二区,TOP期刊]
8. Huang X#, Cao Z#, Ding T, Qian J, Zhang H, Zhong S, Wang X, Yao G, Xu Y, Wen LP*, Yang X*, Zhang Y*. Nanoreceptors promote mutant p53 protein degradation by mimicking selective autophagy receptors. Nature Nanotechnology, 2024, doi: 10.1038/s41565-023-01562-5. [IF:38.3,中科院一区,TOP期刊]
9. Wu Y#, Jiang W#, Huo S#, Li S, Xu Y, Ding S, Zhou J, Liu H, Lv W*, Wang Y*. Nano-metal-organic-frameworks for Treating H2O2-Secreting Bacteria Alleviate Pulmonary Injury and Prevent Systemic Sepsis. Biomaterials, 2021, 279, 121237. [IF:14.0,中科院一区,TOP期刊]
10. Zhu Y#, Zhang H#, Mao H#, Zhong S, Huang Y, Chen S, Yan K, Zhao Z, Hao X, Zhang Y, Yao H, Huang X, Wang M, Zhang W, Li J, Meng G, Qin X, Ye Z, Shen J, Song Y, Xu Y, Yang Z, Wang L*, Zhang Y*, Wen L*. FAAH Served a Key Membrane-Anchoring and Stabilizing Role for NLRP3 Protein Independently of the Endocannabinoid System. Cell Death & Differentiation, 2023, 30, 168-183. [IF:12.4,中科院一区,TOP期刊]
11. Ma Y#, Tang X#, Xu Y, Jiang W, Xin Y, Zhao W, He X, Lu L*, Zhan M*. Nano-enabled Coordination Platform of Bismuth Nitrate and Cisplatin Prodrug Potentiates Cancer Chemoradiotherapy via DNA Damage Enhancement. Biomaterials Science, 2021, 9, 3401-3409. [IF:6.6,中科院二区]
12. Yao H, Zhang Y, Liu, L, Xu Y, Liu X, Lin J, Zhou W, Wei P, Jin P, Wen LP*. Inhibition of Lanthanide Nanocrystal-induced Inflammasome Activation in Macrophages by a Surface Coating Peptide Through Abrogation of ROS Production and TRPM2-Mediated Ca2+ Influx. Biomaterials, 2016, 108, 143-156. [IF:12.4,中科院一区,TOP期刊]