王杰,博士,校聘副教授,硕士生导师
2014年7月毕业于安徽医科大学临床药学专业,获学士学位。博士毕业于福州大学,师从国家千人计划、国际欧亚科学院院士贾力教授,研究方向聚焦于疾病标志物分析检测(外泌体、miRNA、CTCs等),通过利用核酸扩增分子诊断、核酸组装、光电分析、纳米生物传感技术,发展了一系列检测新方法。累计共发表 SCI 论文20余篇,其中第一作者和通讯作者论文17篇,总IF>120,单篇 IF>10 的论文5篇,中科院一区 Top论文10余篇,授权专利2项。
研究方向:疾病早期诊断,DNA纳米自组装,靶向药物递送,光学生物传感
联系方式:wangjienar@163.com
主持课题:
1. 安徽省自然科学基金,S202302c04023125,2024.1-2026.12,在研;
2. 安徽省高校自然科学基金重点项目,2022e07020060,在研;
3. 安徽省重点研究与开发计划,2022e07020060,在研;
4. 2021年引进人才博士科研启动经费,0601095201,在研。
部分发表文章(5篇代表作):
1. Jie Wang,Haiyan Dong, Yuyang Zhou, Longyu Han, Ting Zhang, Min Lin, Chiahung Wang, Huo Xu, ZaiSheng Wu, and Lee Jia. Immunomagnetic antibody plus aptamer pseudo-DNA nanocatenane followed by rolling circle amplication for ultrasensitive CTC detection. Biosensors & Bioelectronics. 2018 Dec 30; 122:239-246.(一区,IF:12.545)
2. Jie Wang, Xiaobo Yu, Huayi Peng, Yusheng Lu, Shuhui Li, Qing Shi, Jian Liu, Haiyan Dong, Vladimir Katanaev, and Lee Jia. Embedding similarities between embryos and circulating tumor cells: fundamentals of abortifacients used for cancer metastasis chemoprevention. Journal of Experimental & Clinical Cancer Research. (2021) 40: 300. (一区,IF:12.658)
3. Jie Wang, Huo Xu, Shuhui Li, Min Lin, Yusheng Lu, Kuancan Liu,Vladimir Katanaev, Evgeny V. Denisov, Lee Jia*. Long cruising aptamer-albumin nanobots intelligently capture and restrain circulating tumor cells. Nano Today 53 (2023) 102002. (一区,IF:17.4)
4. Lizhi Liu, Dingyi Pan, Sheng Chen, Maria-Viola Martikainen, Anna Kårlund, Jing Ke, Herkko Pulkkinen, Hanna Ruhanen, Marjut Roponen, Reijo Käkelä, Wujun Xu,Jie Wang*(通讯), and Vesa-Pekka Lehto*. Systematic design of cell membrane coating to improve tumor targeting of nanoparticles. Nature Communications. 2022. DOI:10.1038/s41467-022-33889-3(一区,IF:17.694)
5. Hehe Tang, Wei Chang, Huijie Xue, Changlu Xu, Zhi Li, Hao Liu, Chao Xing, Gang Liu, Xiaoyan Liu, Hua Wang, Jie Wang*(通讯). Engineered DNA molecular machine for ultrasensitive detection of environmental lead pollution.Journal of hazardous materials. 2023 Oct 5:459:132306.(一区,IF:13.6)