李荣,博士,教授,博士生导师
安徽医科大学中青年学术技术带头人,安徽医科大学“青年拔尖人才支持计划”培育人选,入选安徽省教育厅高校优秀青年人才支持计划。安徽省药物化学专业委员会委员。先后主持2项国家自然科学基金、1项教育部博士学科点专项科研基金和1项省自然科学基金等多项课题研究,发表SCI论文20余篇。教育部黄大年式教师团队主要成员。
研究方向:类风湿关节炎发病机制及药物药理学研究。
联系方式:
邮箱:lirong@ahmu.edu.cn
主持课题:
1. 国家自然科学基金项目(81972040):水通道蛋白1通过Wnt/β-catenin通路调控FLS活化参与类风湿关节炎发病的机制研究,2020.01- 2023.12
2. 安徽省教育厅高校优秀青年人才支持计划重点项目(gxyqZD2016045):水通道蛋白4参与类风湿关节炎关节软骨损伤的机制和功能研究,2016.1-2018.12
3. 国家自然科学基金项目(81102273):Hedgehog-GLi1信号通路在类风湿关节炎关节软骨损伤和修复中的作用及机制研究,2012.1-2014.12
4. 教育部高等学校博士学科点专项科研基金项目(20113420120005):Hedgehog-Gli1通路在类风湿关节炎关节软骨损伤和修复中的作用及机制研究,2012.1-2014.12
5. 安徽省自然科学基金项目(11040606Q15):JAK-STAT途径调控RA滑膜细胞增殖/凋亡及7, 3'-二甲氧基橙皮素的干预机制,2011.1-2012.12
部分发表文章:(10篇以内)
1. Yu-rong Mu#, Meng-yuan Zhou#, Li Cai, Ming-ming Liu, Rong Li*. Overexpression of aquaporin 1 in synovium aggravates rat collagen-induced arthritis through regulating β-catenin signaling: an in vivo and in vitro study. J Inflamm Res. 2020, 13: 701-712. 通讯作者
2. Zhong-zhen Zhu, Yu Qiao, Zi-hao Zhang, Ming-zhen Gu, Jin Wang, Zhi-yu Gao, Wen-hao Guo, Ming-ming Liu, Rong Li*. Design, synthesis and antitumor evaluation of novel small molecule extracellular regulated protein kinase (ERK) inhibitors. Chinese J Org Chem. 2020, 40 (7), 1983-1990. ISSN: 0253-2786. 通讯作者
3. Li Cai#, Yu-rong Mu#, Ming-ming Liu, Wen-jian Tang, Rong Li*. Antidepressant-like effects of penta-acetyl geniposide in chronic unpredictable mild stress-induced depression rat model: Involvement of inhibiting neuroinflammation in prefrontal cortex and regulating hypothalamic-pituitaryadrenal axis. Int Immunopharmacol. 2020, 80: 106182. 通讯作者
4. Li Cai#, Chun-mei Li#, Wei-na Chen, Yuan-ye Qiu, Yan-li Guo, Rong Li*. Penta-acetyl geniposide induces apoptosis of fibroblast-like synoviocytes from adjuvant-induced arthritis rats in vitro, associated with inhibition of NF-κB activation. Pharmacological Reports. 2019, 71(6):1006-1013. 通讯作者
5. Li Cai#, Chun-mei Li#, Wen-jian Tang, Ming-ming Liu, Wei-na Chen, Yuan-ye Qiu, Rong Li*. Therapeutic effect of penta-acetyl geniposide on adjuvant-induced arthritis in rats: Involvement of inducing synovial apoptosis and inhibiting NF-κB signal pathway. Inflammation. 2018, 41(6): 2184-2195. ISSN: 0360-3997通讯作者
6. Rong Li#, Xia Zhao#, Li Cai*, Wan-wan Gao. Up-regulation of GluR1 in paraventricular nucleus and greater expressions of synapse related proteins in the hypothalamus of chronic unpredictable stress-induced depressive rats. Physiol Behav. 2017, 179: 451-457. 第一作者
7. Li Cai#, Chao Lei#, Rong Li*, Wei-na Chen, Cheng-mu Hu, Xiao-yu Chen, Chun-mei Li. Overexpression of aquaporin 4 in articular chondrocytes exacerbates the severity of adjuvant-induced arthritis in rats: an in vivo and in vitro study. J Inflamm (Lond). 2017, 14: 6. 通讯作者
8. Rong Li, Li Cai*, Wen-jian Tang, Chao Lei, Cheng-mu Hu, Fang Yu. Apoptotic effect of geniposide on fibroblast-like synoviocytes in rats with adjuvant-induced arthritis via inhibiting ERK signal pathway in vitro. Inflammation. 2016, 39(1): 30-38. 第一作者
9. Li Cai, Rong Li*, Wen-jian Tang, Gang Meng, Xiang-yang Hu, Ting-ni Wu. Antidepressant-like effect of geniposide on chronic unpredictable mild stress-induced depressive rats by regulating the hypothalamus-pituitary-adrenal axis. Eur Neuropsychopharmacol. 2015, 25(8): 1332-1341. 通讯作者
10. Rong Li, Li Cai*, Jing Ding, Cheng-mu Hu, Ting-ni Wu, Xiang-yang Hu. Inhibition of hedgehog signal pathway by cyclopamine attenuates inflammation and articular cartilage damage in rats with adjuvant-induced arthritis. J Pharm Pharmacol. 2015, 67(7): 963-971. 第一作者
获奖:
安徽省首届优秀硕士学位论文
安徽省第七届自然科学优秀学术论文二等奖
安徽省第八届自然科学优秀学术论文二等奖