药剂学
硕士生导师——汤继辉教授
文章来源:药学院    发布时间:2015-12-11

    


汤继辉药剂学博士,教授,硕导

药学院教工第一党支部书记,药剂学教研室副主任(主持工作),安徽医科大学附属亳州医院(亳州市人民医院)挂职副院长(2022.7.1-),安徽医科大学第三批安徽医科大学校级优秀青年教师。安徽省药剂学专业委员会委员,安徽省医学会肠外肠内营养学分会营养药学学会委员,Current Drug Targets杂志客座编辑,《安徽医药》杂志编委,《International Journal of Pharmaceutics》、《Drug DeliveryInternational Journal of Nanomedicine等杂志审稿人。主持国家自然科学基金、安徽省自然科学基金等多项课题研究,发表SCI论文20余篇。省级精品资源共享课程《药剂学》、《生物药剂学与药物动力学》的主讲教师,参编国家级规划教学《药剂学》、《工业药剂学》、《药学概论》等。


 

主要研究方向:智能响应型靶向制剂、新型高端制剂。

联系方式:flying.99@163.com


主持课题:

1.安徽省药品监管科学研究重点项目(基于药物吸收建立的新型溶出方法及其用于药物质量监测的研究,编号 AHYJ-KJ-202206)2023.1-2024.12,10万元,在研,主持

2.安徽高校自然科学研究项目基于磷脂酰丝氨酸特异性识别肽及pH敏感双靶向制剂的研究,编号:KJ2020A0157),2021.01-2023.126万元,在研,主持

3.新安医学教育部重点实验室开放基金中药桔梗对荆芥载药上浮作用物质基础及机制研究,编号:2020xayx02),2021.01-2023.126万元,在研,主持

4.国家自然科学基金青年基金,81503004,针对肿瘤细胞周期的时相靶向制剂的研究,2016.01-2018.1217.9万元,已结题,主持

5.安徽省自然科学基金,1408085QH189基于叶酸修饰聚合物胶束的细胞周期特异性靶向给药系统的研究2014/07-2016/067万元已结题主持

6.安徽省高校省级优秀人才基金重点项目,2013SQRL019ZD叶酸修饰聚氨基酸胶束主动靶向给药系统的研究2014/01-2016/129万元已结题主持

 

部分发表文章:(10篇以内)

1Jianwei Bao, Minxing Hu, Yuanmei Zhang, Qianqian Zhang, Feiyan Zhu, Qianli Zou*, Jihui Tang*. Novel active stealth micelles based on β2M achieved effective antitumor therapy.Biomedicine & Pharmacotherapy. 2022,151,113175.

2Qianqian Zhang, Jianwei Bao, Tijie Duan, Minxing Hu, Yuting He, Junwei Wang, Rongfeng Hu*, Jihui Tang*. Nanomicelle-Microsphere Composite as a Drug Carrier to Improve Lung-Targeting Specificity for Lung Cancer, Pharmaceutics, 2022, 14(3): 510

3Bo Li, Tingfei Tan, Weiwei Chu, Ying Zhang, Yuanzi Ye, Shanshan Wang, Yan Qin, Jihui Tang*, Xi Cao*. Co-delivery of paclitaxel (PTX) and docosahexaenoic acid (DHA) by targeting lipid nanoemulsions for cancer therapy. Drug Delivery,2022, 29 (1):75-78.

4Jianwei Bao, Qianqian Zhang, Tijie Duan,Rongfeng Hu, Jihui Tang*. The Fate of Nanoparticles In Vivo and the Strategy of Designing Stealth Nanoparticle for Drug Delivery. Curr Drug Targets, 2021,22(8):922-946

5Siyu Guan, Qianqian Zhang, Jianwei Bao, Tijie Duan, Rongfeng Hu, Tori Czech, Jihui Tang*.Phosphatidylserine targeting peptide-functionalized pH sensitive mixed micelles for enhanced anti-tumor drug delivery. European Journal of Pharmaceutics and Biopharmaceutics. 2020,147:87-101. 

6Siyu Guan, Qianqian Zhang, Jianwei Bao, Rongfeng Hu, Tori Czech, Jihui Tang*.Recognition Sites for Cancer-targeting Drug Delivery Systems. Current Drug Metabolism. 2019;20(10):815-834. 

7Jihui Tang*, Jie Ning, Xiaoyan Liu, Baoming Wu, Rongfeng Hu*. A Novel Amino Acid Sequence-based Computational Approach to Predicting Cell-penetrating Peptides. Current computer-aided drug design. 2019,15(3):206-211.

8)Wenxiu Hong, Rongfeng Hu, Xuechao Huang, Xiaoqian Lu, Tori Czech, Jihui Tang*. In vivo pharmacokinetics and biodistribution of novel all-trans retinoic acid derivative-loaded, folate-modified poly (L-amino acid) micelles. Journal of Drug Delivery Science & Technology. 2017, 41: 436-43.

9Jihui Tang, Ziwei Liu, Fenqi Ji, Yao Li, Junjie Liu, Jian Song, Jun Li*, Jianping Zhou*. The role of the cell cycle in the cellular uptake of folate-modified poly (L-amino acid) micelles in a cell population. Nanoscale. 2015, 7(48): 20397-404. 

10)Jihui Tang*, Xinqun Wang, Ting Wang, Feihu Chen, Jianping Zhou. In vivo pharmacokinetics, biodistribution and antitumor effect of amphiphilic poly(L-amino acids) micelles loaded with a novel all-trans retinoic acid derivative. European Journal of Pharmaceutical Sciences, 2014, 51(1): 157-64.


获奖/专利

1) 汤继辉,李俊,刘紫薇,宋见,纪玢琪,李瑶,刘俊节.一种肿瘤靶向聚合物胶束及其制备方法, 2017.10.27,中国:ZL201510475783.3(授权)

2) 汤继辉,韩治敏,何佳琪,柳圆圆,郑层层.一种紫杉醇粉雾剂的制备方法,中国专利:ZL201810603428.3(授权)

3) 汤继辉,管思宇,洪文秀,梅雪,黄淼.一种肿瘤靶向和pH响应的聚合物胶束及其制备方法,中国专利:CN201811248768.5(申请)

4) 汤继辉,张倩倩,鲍健威,段体杰,何雨婷.一种肿瘤靶向给药系统,中国专利:CN202011016923.8(申请)

5)汤继辉,安徽医科大学2015年度十大科技新星,安徽医科大学,2015

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