黄晓晖,博士,教授,博士生导师
1973年6月出生,皖江学者特聘教授,安徽省学术技术带头人。近年在J Cardiovasc Pharmacol、GENE、Eur J Drug Metab Pharmacokinet等学术期刊上发表论文71余篇(一作和通讯59篇),SCI源期刊收录20余篇,主编和主译专著2部(《定量药理与新药评价》、《新药研发的剂量优化》)、参编专著十余部,主持国家自然科学基金2项、中国博士后基金、省自然科学基金、省优秀青年科技基金、安徽省学术技术带头人科研经费资助等项目8项。获得安徽省科技进步二等奖、安徽省青年科技奖、安徽省科技进步三等奖等科研奖励。担任中国药理学会定量药理专业委员会委员、中国临床药理学与治疗学杂志编委、安徽省预防医学会卫生统计专业委员会常委、安徽省医药生物技术协会理事等学术职务。
研究方向:定量药理学、临床药动学。
联系方式: aydice@126.com
主持课题:
1. 国家自然科学基金(81173133):应用药效学比例预测与药动学-药效学模型研究药物联用的剂量优化--以华法林和阿司匹林联用为例,2012-2015(National Natural Science Fund of China)
2. 国家自然科学基金(30701040):应用群体PK-PD模型进行基于基因多态性的个体化用药剂量设计-以华法林为例, 2007-2010
3. 安徽省优秀青年科技基金(08040106813),2008-2010
4. 安徽省自然科学基金(070413117)VKORC1基因多态性与华法林个体化剂量关系的群体PK-PD模型,2008-2010
部分发表文章:(10篇以内)
1. Caifen Qi, Shuangli Xu , Maomao Wu, Shuo Zhu, Yanyan Liu , Hong Huang, Guijun Zhang, Jiabin Li, Xiaohui Huang. Pharmacodynamics Of Linezolid-Plus-Fosfomycin Against Vancomycin-Susceptible And -Resistant Enterococci In Vitro And In Vivo Of A Galleria mellonella Larval Infection Model. Infect Drug Resist. 2019, 12;12:3497-3505
2. Lan Li, Hao Chen, Yanyan Liu, Shuangli Xu, Maomao Wu, Zhou Liu, Caifen Qi, Guijun Zhang, Xiaohui Huang. Synergistic effect of linezolid with fosfomycin against Staphylococcus aureus in vitro and in an experimental Galleria mellonella model. Journal of Microbiology, Immunology and Infection. J Microbiol Immunol Infect. 2018, 31;S1684-1182
3. XF Xie, LS Yang, AZ Shen, XH Huang, XY Chen, J Li, YH Sun. Influential factors of physicians’ prescription behavior in selecting essential medicines: a cross-sectional survey in Chinese county hospitals. Primary Health Care Research & Development.2019, 19:980-988
4. XF Xie, XH Huang,AZ Shen, J Li, YH Sun. Association between circulating leptin levels and multiple sclerosis: A systematic review and meta-analysis. Postgrad Med J 2018;94:278–283.
5. Hao Chen, Lan Li,Yanyan Liu,Maomao Wu, Shuangli Xu, Guijun Zhang, Caifen Qi,Yan Du, Mingli Wang, Jiabin Li, Xiaohui Huang. In vitro activity and post-antibiotic effects of linezolid in combination with fosfomycin against clinical isolates of Staphylococcus aureus
6. Infection and Drug Resistance. 2018:11 2107–2115
7. Hao Chen, Lan Li, Shuai Song, Yan Du, Xiaoqin Jin, PeiPei Ding, Chenlin Shen, and Xiaohui Huang. Determination of lacidipine in human plasma by LC-MS/MS: Application in a bioequivalence study International Journal of Clinical Pharmacology and Therapeutics, 2018 , 56(10):493-500
8. Chenlin Shen , Xiaoqin Jin, Maomao Wu, Xiaohui Huang, Jun Li, Hong Huang, Feilong Li, Jiatao Liu, Genxiang Rong, Shuai Song. A Sensitive LC-MS/MS Method to Determine Ginkgolide B in Human Plasma and Urine: Application in a Pharmacokinetics and Excretion Study of Healthy Chinese Subjects. Xenobiotica . 2020,50(3):323-331.
9. Min Yang, Tianfeng Hua,Zhengfei Yang, Limin Chen, Yangyang Zou, Xiaohui Huang, and Jun Li. The Protective Effect of rhBNP on Postresuscitation Myocardial Dysfunction in a Rat Cardiac Arrest Model.Biomed Res Int. 2020, 17;2020:6969053.
10. P Zhang, C Wu, XH Huang, CL Shen, L Li, W Zhang, CZ Yao. Aspirin suppresses TNF-α-induced MMP-9 expression via NF-κB and MAPK signaling pathways in RAW264.7 cells . Experimental & Therapeutic Medicine, 14: 5597-5604, 2017