药物分析学
硕士生导师——余欢副教授
文章来源:药学院    发布时间:2022-10-21


余欢,博士,副教授,硕士生导师

主持国家自然科学基金面上项目,青年项目各一项,主持安徽省高校优秀青年科研项目一项。主持省自然科学基金面上项目,高等学校自然科学研究重点项目,以及国家重点实验室开放课题等。作为项目骨干,参与国家自然科学基金委重大研究计划培育项目和多个面上项目。发表SCI论文三十多篇,以第一作者(包括共同一作)和通讯作者发表SCI论文16篇,其中中科院一区论文9篇。获得2018年中国分析测试协会科学技术奖二等奖(R3),2020年中国发明协会发明创新奖二等奖(R3

 

邮箱:hyu@ahmu.edu.cn

 

研究方向:

主要从事功能有机分子探针的设计与合成、纳米材料的制备与功能化、及其在分析化学、药物分析和环境分析方面的应用。以生物活性分子(活性氮氧化合物、气体信号分子,功能酶,DNA, RNA)以及药物分子(药物残留,药效监测,药物筛选)的高灵敏检测为目标,发展基于有机分子和纳米材料的新型传感原理与方法,研究其在生理与病理过程中的作用。进一步研发有机纳米复合传感器件,为重要目标物的检测提供廉价、安全、快速和有效的新技术手段。

 

主持的科研项目:

1. 国家自然科学基金面上项目,222760012023.01-2026.12,主持,在研

2. 安徽省高校优秀青年项目:2023.09-2026.09,主持,在研

3. 2018年引进人才博士科研启动经费,XJ201825,主持,在研

4. 2019年化学生物传感与计量学国家重点实验室开放课题,2019015,主持,已结题

5. 国家自然科学基金青年基金,215071352016.01-2018.12,主持,已结题

6. 安徽省自然科学基金面上项目,1608085MB302016.07-2018.06,主持,已结题

7. 安徽医科大学药学院高峰学科建设人才经费:2022.06-2024.05,主持,在研

 

发表论文:

1Lei Wen, Xinyu Ma, Jing Yang, Minmin Jiang, Chao Peng, Zhongyun Ma, Huan Yu*, Yinhui Li*, A New Ratiometric Design Strategy Based on Modulation of π-Conjugation Unit for Developing Fluorescent Probe and Imaging of Cellular Peroxynitrite, Analytical Chemistry. 2022, 94, 11, 4763-4769

2Hufeng Fang, Huan Yu*, Qi Lu, Xun Fang, Qunlin Zhang*, Junting Zhang, Lili Zhu, Quanbao Ma, A New Ratiometric Fluorescent Probe for Specific Monitoring of hROS under Physiological Conditions Using Boric Acid-Protected L-DOPA Gold Nanoclusters, Analytical Chemistry, 2020, 92, 12825-12832.

3Huan Yu, Libo Du, Lingmei Guan, Kui Zhang, Yingyun Li, Houjuan Zhu, Mingtai Sun, Suhua Wang*, A Ratiometric Fluorescent Probe Based on the Pi-Stacked Graphene Oxide and Cyanine Dye for Sensitive Detection of Bisulfite, Sensors and Actuators B-Chemical, 2017, 247, 823-829.

4Huan Yu, Mingtai Sun, Kui Zhang, Houjuan Zhu, Jun Zhao, Zhengjie Liu, Zhongping Zhang, Suhua Wang*. A Reversible Near- Infrared pH Probes for Optical Measurements of pH in Complete Water System and Live Cells, Sensors and Actuators B: Chemical, 2015, 219, 294-300.

5Huan Yu, Xinfeng Chen, Long Yu, Mingtai Sun, Khalid A. Alamry, Abdullah M. Asiri, Kui Zhang, Juan Antonio Zapien, Suhua Wang*, Fluorescent MUA-Stabilized Au Nanoclusters for Sensitive and Selective Detection of Penicillamine, Analytical and Bioanalytical Chemistry, 2018, 410, 2629-2636.

6Huan Yu, Jing Zheng, Sheng Yang, Abdullah M. Asiri, Khalid A. Alamry, Mingtai Sun, Kui Zhang, Suhua Wang*, Ronghua Yang*, Use of a Small Molecule as an Initiator for Interchain Staudinger Reaction: A New ATP Sensing Platform Using Product Fluorescence, Talanta, 2018, 178, 282-286.

7Yingyun Li, Mingtai Sun, Kui Zhang, Yajun Zhang, Yehan Yan, Kepeng Lei, Lijun Wu, Huan Yu*, Suhua Wang*, A Near-Infrared Fluorescent Probe for Cu2+ in Living Cells Based on Coordination Effect, Sensors and Actuators B-Chemical, 2017, 243, 36-42.

8Tianxin Hou, Kui Zhang, Xiaoxuan Kang, Xueling Guo, Libo Du, Xinfeng Chen, Long Yu, Ji Yue, Hongwei Ge, Yang Liu, Abdullah M. Asiri, Khalid A. Alamry, Huan Yu*, Suhua Wang*, Sensitive Detection and Imaging of Endogenous Peroxynitrite Using a Benzo [d] Thiazole Derived Cyanine Probe, Talanta, 2019, 196, 345-351.

9Yehan Yan#, Huan Yu#, Yajiao Zhang, Kui Zhang, Houjuan Zhu, Tao Yu, Hui Jiang, Suhua Wang*, Molecularly Engineered Quantum Dots for Visualization of Hydrogen Sulfide, ACS Appl. Mater. Interfaces, 2015, 7, 35473553.

10Mingtai Sun#, Huan Yu#, Kui Zhang, Suhua Wang, Tasawar Hayat, Ahmed Alsaedi, Dejian Huang, Palladacycle Based Fluorescence Turn-On Probe for Sensitive Detection of Carbon Monoxide, ACS Sensors, 2018, 3, 285-289.