药物化学
硕士生导师——崔昊副教授
文章来源:药学院    发布时间:2023-09-20


崔昊,药物化学博士,校聘副教授,硕士生导师,毕业于中国药科大学,主要研究方向为小分子抗肿瘤药物的设计、合成及生物活性研究。参与多项国家自然基金项目及省级项目。

 

联系方式:cuih1008@ahmu.edu.cn

 

主要科研项目:

安徽省高校自然科学研究项目,2022AH0506542023.1-2024.12,主持;

2022年引进人才博士科研启动经费,0601113201

 

主要发表论文:

Hao Cui#, Qianqian Hong#, Ran Wei, Hongmei Li, Chunyang Wan, Xin Chen, Shuang Zhao, Haizhi Bu, Bingxu Zhang, Dexiao Yang, Tao Lu*, Yadong Chen*, Yong Zhu*. Design and synthesis of HDAC inhibitors to enhance the therapeutic effect of diffuse large B-cell lymphoma by improving metabolic stability and pharmacokinetic characteristics. European Journal of Medicinal Chemistry. 2022 5(229): 114049.

Hao Cui, Jingkun Huang, Yan Lei, Quanwei Chen, Zan Hu, Jiaqi Niu, Ran Wei, Kang Yang, Hongmei Li, Tao Lu*, Yong Zhu*, Yatian Huang*. Design and synthesis of dual inhibitors targeting snail and histone deacetylase for the treatment of solid tumour cancer. European Journal of Medicinal Chemistry. 2022 5(229): 114082.

Hao Cui#, Zan Hu#, Kang Yang, Jingkun Huang, Yichao Wu, Quanwei Chen, Ran Wei, Penfeng Wang, Hui Wang, Tao Lu*, Yuqin Yao*, Yong Zhu*. Design and synthesis of highly TRAIL expression HDAC inhibitors based on ONC201 to promote apoptosis of colorectal cancer. European Journal of Medicinal Chemistry. 2022 10(238): 114568.