中药学
硕士生导师-陈岩
文章来源:药学院    发布时间:2023-03-02


陈岩,博士,博士后,校聘副教授,硕士生导师

博士毕业于中山大学,主要开展中药植物及其内生真菌来源的新颖结构物质及其药理活性研究,先后以第一作者和通讯作者在Org. Lett.J. Nat. Prod.Bioorg. Chem.Front. Microbiol., Mar. DrugsTetrahedron Lett.等国际知名期刊上发表学术论文11篇,主持并参与多项国家自然科学基金项目及省级项目。


研究方向:中药植物及其内生真菌来源次级代谢产物活性成分研究


联系方式cychemistry@163.com


代表文章

  1. Yan Chen, Wencong Yang, Ge Zou, Guisheng Wang, Wenyi Kang, Jie Yuan*, Zhigang She*. Cytotoxic Bromine- and Iodine-Containing Cytochalasins Produced by the Mangrove Endophytic Fungus Phomopsis sp. QYM-13 Using the OSMAC Approach. Journal of Natural Products 2022, 85, 1229-1238.

  2. Yan Chen, Hongju Liu,Wencong Yang,Lishan Zhang, Ge Zou, Changqun Li,Zhangyuan Yan, Yuhua Long and Zhigang She*. Bioactive Sesquiterpene Derivatives from Mangrove Endophytic fungus Phomopsis sp. SYSU-QYP-23: Structures and Nitric Oxide Inhibitory Activities. Bioorganic Chemistry 2021, 107, 104530.

  3. Yan Chen, Lishan Zhang, Ge Zou, Changqun Li, Wencong Yang, Hongju Liu, Zhigang She*. Anti-inflammatory Activities of Alkaloids from the Mangrove Endophytic Fungus Phomopsis sp. SYSU-QYP-23. Bioorganic Chemistry 2020, 97, 103712.

  4. Yan Chen, Zhaoming Liu, Yun Huang, Lan Liu, Jianguo He, Lan Wang, Jie Yuan, Zhigang She*. Ascomylactams A–C, Cytotoxic 12-or 13-Membered-Ring Macrocyclic Alkaloids Isolated from the Mangrove Endophytic Fungus Didymella sp. CYSK-4, and Structure Revisions of Phomapyrrolidones A and C. Journal of Natural Products 2019, 82, 1752-1758.

  5. Zhaoming Liu#, Yan Chen#, Shenhua Chen, Yayue Liu, Yongjun Lu, Dongni Chen, Yongcheng Lin, Xishan Huang, Zhigang She*. Aspterpenacids A and B, Two Sesterterpenoids from a Mangrove Endophytic Fungus Aspergillus terreus H010. Organic Letters 2016, 18, 1406-1409. (Co-first Author)


授权专利

佘志刚,陈岩,袁洁,汪兰, 刘昭明,黄韵。 一株阔苞菊内生真菌CYSK 4及其生产的Ascomylactam类化合物的应用。2018,中国,CN107686817A


主要科研项目

  1. 安徽省高校自然科学科研项目:2023.01-2024.12,主持,在研

  2. 安徽医科大学人才启动项目:2022.08-2027.07,主持,在研